FALLER Peter, University of Strasbourg – CNRS, France
Redox Reactivity of Cu-Peptides: Mechanism, Detection and Interference
Biography:
Peter Faller is Professor in Chemistry at the University of Strasbourg (France) and Group Leader at the Institute of Chemistry. He studied at the University of Zürich (Switzerland) earning a PhD in biochemistry on metallothioneins in 1998 with Prof. M. Vasak. He did his postdoctoral studies on photosystem II at the CEA near Paris (France) with Dr. Bill Rutherford and in Freiburg (Germany) with Dr. Anja Krieger-Liszkay. In 2003 he was appointed professor and group leader at the LCC (Coordination Chemistry Laboratory of the CNRS) in Toulouse (France), where he stayed more than a decade, mainly working in bioinorganics on the role of essential d-block metal ions in the aggregation and toxicity of the peptide amyloid-beta linked to Alzheimer’s disease. In 2015 he moved to the Chemistry Institute at the University Strasbourg.
Ongoing research projects of his group in bioinorganics on the development of copper(II) sensors for detection in a biological medium, mechanistic studies of chelators complexed with copper, zinc or iron in their anticancer and antimicrobial activity, reactivity of copper-amyloidogenic peptides, and the development of hybrids of peptides and metal-complexes for therapeutic approaches.