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HOSTACHY Sarah, CEA-Grenoble, France

Uranyl-binding peptides to investigate uranium toxicity at the molecular level


Sarah Hostachy studied chemistry and systems biology at Ecole Normale Supérieure and Université Pierre et Marie Curie in Paris, France. She completed her Ph. D. under the supervision of Prof. Clotilde Policar and Dr. Nicolas Delsuc (2015), on the development of rhenium complexes for the multimodal imaging of peptides and proteins. She then joined the group of Prof. Dorothea Fiedler as a postdoctoral fellow at the Leibniz-Institut für Molekulare Pharmakologie (Berlin, Germany), where she developed chemical tools to interrogate the roles of inositol polyphosphates in biology. In 2020, she was appointed CEA researcher at the SyMMES laboratory in Grenoble, France. She is interested in chemical biology approaches to investigate metal-protein interactions, with a particular focus on f-elements.