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JANCSO Attila, University of Szeged, Hungary

AsIII and HgII binding at the metal site of an arsenic responsive metalloregulator and the molecular details of metalloid recognition


Attila Jancsó is an associated professor at the Department of Molecular and Analytical Chemistry, University of Szeged where he obtained his diploma in chemistry in 1997 and a PhD degree in 2002, also in chemistry. He spent 2 years as a postdoctoral fellow in Prof. Harri Lönnberg’s lab. at the University of Turku, working on metal complexes as structural and functional mimics of phosphoesterase enzymes. His recent research is focused on the metal ion / metalloid binding by peptide models of bacterial metalloregulators, as well as the native proteins, with an aim to explore the relationship between metal(loid) site structures, metal ion / metalloid recognition and the mechanism of action of the studied metalloregulatory proteins. Attila Jancsó’s scientific interest is also devoted to characterizing the interaction of the trivalent forms of Group V metalloids (arsenic(III) and antimony(III)) with various thiol ligands covering structure, binding affinity and speciation and the role these may play in their bio(inorganic)chemistry.